Gold-Catalyzed Redox Synthesis of ImidazoACHTUNGTRENNUNG[1,2-a]pyridines using Pyridine N-Oxide and Alkynes
نویسندگان
چکیده
A mild, catalytic, atom economical synthesis of imidazo ACHTUNGTRENNUNG[1,2-a]pyridines has been developed: catalytic dichloro(2-pyridinecarboxylato)gold [PicAuCl2] in the presence of an acid produces a range of imidazo ACHTUNGTRENNUNG[1,2-a]pyridines in good yields starting from alkynes and 2-aminopyridine Noxides. This strategy is mild and foreseen to be of particular use for the installation of stereogenic centers adjacent to the imidazoACHTUNGTRENNUNG[1,2-a]pyridine ring without loss of enantiomeric excess.
منابع مشابه
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